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\u3000<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

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\u767b\u4e0a\u7dda\u7dad\u306fMLI1\u3060\u3051\u3067\u306a\u304f\u3001\u3082\u3046\u4e00\u3064\u306e\u4ecb\u5728\u30cb\u30e5\u30fc\u30ed\u30f3\u3001MLI2\u306b\u3082\u89e6\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

MLI2\u306f\u30d7\u30eb\u30ad\u30f3\u30a8\u7d30\u80de\u3092\u76f4\u63a5\u6291\u3048\u305a\u3001MLI1\u3092\u6291\u3048\u308b\u5074\u3067\u3059\u3002<\/p>\n\n\n\n

\u3064\u307e\u308a\u3001\u9580\u756a\u3092\u62bc\u3055\u3048\u308b\u5f79\u3067\u3059\u3002<\/p>\n\n\n\n

\u4e00\u672c\u306e\u767b\u4e0a\u7dda\u7dad\u304c\u89e6\u308c\u308b\u7d30\u80de\u6570\u306fMLI1\u3068MLI2\u3067\u307b\u307c\u540c\u3058\u306a\u306e\u306b\u3001\u63a5\u89e6\u70b9\u306e\u6570\u306fMLI2\u3067\u7d042.4\u500d\u591a\u304f\u3001\u63a5\u89e6\u9762\u7a4d\u3082\u5e83\u3044\u3002<\/p>\n\n\n\n

\u96fb\u6c17\u751f\u7406\u3067\u3082\u3001MLI2\u306f26\u7d30\u80de\u4e2d25\u7d30\u80de\u3067\u306f\u3063\u304d\u308a\u5fdc\u7b54\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001MLI1\u3067\u306f\u53cd\u5fdc\u306f\u304b\u306a\u308a\u5f31\u3044\u3082\u306e\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

\u5b66\u7fd2\u306e\u5408\u56f3\u306f\u3001\u307e\u305a\u9580\u756a\u305d\u306e\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u9580\u756a\u3092\u6291\u3048\u308b\u5074\u3092\u512a\u5148\u3057\u3066\u52d5\u304b\u3057\u3066\u3044\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

\u3053\u306e\u6d41\u308c\u306f\u3001\u52d5\u3044\u3066\u3044\u308b\u8133\u3067\u3082\u5d29\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

\u81ea\u767a\u7684\u306a\u767b\u4e0a\u7dda\u7dad\u6d3b\u52d5\u306e\u3042\u3068\u3001MLI2\u306f\u767a\u706b\u3092\u5897\u3084\u3057\u3001MLI1\u306f\u6291\u3048\u3089\u308c\u3001\u8fd1\u304f\u306e\u30d7\u30eb\u30ad\u30f3\u30a8\u7d30\u80de\u306f\u6291\u5236\u304b\u3089\u89e3\u653e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u305f\u3060\u3057\u3001\u611f\u899a\u523a\u6fc0\u304c\u5165\u308b\u5834\u9762\u3067\u306f\u8a71\u304c\u6df7\u307f\u5408\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u5225\u306e\u5165\u529b\u7cfb\u3082MLI1\u3092\u62bc\u3057\u4e0a\u3052\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n

\u958b\u3051\u305f\u3044\u529b\u3068\u9589\u3081\u305f\u3044\u529b\u304c\u540c\u6642\u306b\u50cd\u304f\u3002<\/p>\n\n\n\n

\u305d\u306e\u7db1\u5f15\u304d\u3092\u6c7a\u3081\u3066\u3044\u305f\u306e\u304c\u3001\u767b\u4e0a\u7dda\u7dad\u3069\u3046\u3057\u306e\u540c\u671f\u3067\u3057\u305f\u3002<\/p>\n\n\n\n

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\u3000<\/p>\n\n\n\n

\u305d\u306e\u5148\u3067\u3001\u30d7\u30eb\u30ad\u30f3\u30a8\u7d30\u80de\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u4fe1\u53f7\u306f\u5b9f\u969b\u306b\u5927\u304d\u304f\u306a\u3063\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

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\u3051\u308c\u3069\u3001\u8fd1\u304f\u306e\u767b\u4e0a\u7dda\u7dad\u304c\u540c\u6642\u306b\u52d5\u3044\u305f\u3068\u304d\u306b\u306f\u3001\u5358\u767a\u306e\u53cd\u5fdc\u3067\u3082\u30ab\u30eb\u30b7\u30a6\u30e0\u4fe1\u53f7\u304c\u5897\u3048\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u305d\u306e\u52b9\u679c\u304c\u76ee\u7acb\u3063\u305f\u306e\u306f\u3001\u304a\u3088\u305d60\u30de\u30a4\u30af\u30ed\u30e1\u30fc\u30c8\u30eb\u4ee5\u5185\u3067\u3001\u5468\u56f2\u3067\u540c\u6642\u306b\u52d5\u304f\u679d\u304c\u591a\u3044\u307b\u3069\u5897\u5f37\u3082\u5927\u304d\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u5b66\u7fd2\u306f\u3001\u5f37\u3044\u5408\u56f3\u304c\u4e00\u767a\u5165\u308c\u3070\u59cb\u307e\u308b\u306e\u3067\u306f\u306a\u3044\u3088\u3046\u3067\u3059\u3002<\/p>\n\n\n\n

\u5c11\u3057\u524d\u306b\u3001\u90aa\u9b54\u3092\u3057\u3066\u3044\u305f\u6291\u5236\u304c\u3069\u304f\u3002<\/p>\n\n\n\n

\u305d\u306e\u77ed\u3044\u6642\u9593\u304c\u3042\u3063\u3066\u3001\u3088\u3046\u3084\u304f\u66f8\u304d\u63db\u3048\u304c\u5165\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

\u3082\u3061\u308d\u3093\u3001\u3053\u308c\u306f\u30de\u30a6\u30b9\u5c0f\u8133\u306e\u57fa\u790e\u7814\u7a76\u3067\u3059\u3002<\/p>\n\n\n\n

\u96fb\u5b50\u9855\u5fae\u93e1\u306e\u518d\u69cb\u7bc9\u306f\u5358\u4e00\u500b\u4f53\u306b\u57fa\u3065\u3044\u3066\u304a\u308a\u3001MLI2\u3060\u3051\u3092\u9078\u3093\u3067\u6b62\u3081\u308b\u6c7a\u5b9a\u6253\u306e\u5b9f\u9a13\u306f\u3053\u308c\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n

\u305d\u308c\u3067\u3082\u3001\u3053\u306e\u7814\u7a76\u306f\u300c\u7a81\u7136\u3067\u304d\u305f\u300d\u3068\u3044\u3046\u611f\u899a\u306e\u898b\u3048\u65b9\u3092\u5909\u3048\u307e\u3059\u3002<\/p>\n\n\n\n

\u4e0a\u9054\u3068\u306f\u3001\u305d\u306e\u5834\u3067\u65b0\u3057\u3044\u529b\u304c\u8db3\u3055\u308c\u308b\u3053\u3068\u3060\u3051\u3067\u306f\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

\u6628\u65e5\u3068\u4eca\u65e5\u306e\u5dee\u306f\u3001\u80fd\u529b\u306e\u5dee\u3067\u306f\u306a\u304f\u3001\u9589\u3058\u3066\u3044\u305f\u9580\u304c\u6570\u30df\u30ea\u79d2\u3060\u3051\u958b\u3044\u305f\u5dee\u3060\u3063\u305f\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

\u3000<\/p>\n\n\n\n

\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/p>\n\n\n\n

Santos-Valencia F, Lackey EP, Norton A, et al. Climbing fibres recruit disinhibition to enhance Purkinje cell calcium signals. Nature<\/em>. Published online March 18, 2026. doi:10.1038\/s41586-026-10220-4<\/strong><\/p>\n\n\n\n

\u3000<\/p>\n\n\n

\n
\"\"<\/figure>\n<\/div>\n\n\n

\u3000<\/p>\n\n\n\n

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