{"id":28952,"date":"2026-02-20T02:44:00","date_gmt":"2026-02-19T17:44:00","guid":{"rendered":"https:\/\/sakuda-clinic.com\/doctor\/?p=28952"},"modified":"2026-02-13T14:59:26","modified_gmt":"2026-02-13T05:59:26","slug":"%e5%82%b7%e3%81%af%e3%80%81%e3%81%a9%e3%81%93%e3%81%a7%e6%9c%80%e5%88%9d%e3%81%ab%e6%b0%97%e3%81%a5%e3%81%8b%e3%82%8c%e3%82%8b%e3%81%ae%e3%81%8b%e2%80%95%e3%83%9e%e3%82%af%e3%83%ad%e3%83%95%e3%82%a1","status":"publish","type":"post","link":"https:\/\/sakuda-clinic.com\/doctor\/?p=28952","title":{"rendered":"\u50b7\u306f\u3001\u3069\u3053\u3067\u6700\u521d\u306b\u6c17\u3065\u304b\u308c\u308b\u306e\u304b\u2015\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u6838\u304c\u8aad\u307f\u53d6\u308b\u201c\u5f62\u201d\u306e\u5909\u5316\u3068\u5373\u6642\u8840\u7ba1\u5fdc\u7b54"},"content":{"rendered":"\n<p>\u3000<\/p>\n\n\n\n<p>\u300c\u305d\u3053\u3001\u8033\u306e\u5f8c\u308d\u3001\u5c11\u3057\u8840\u304c\u51fa\u3066\u308b\u3088\u300d<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u305d\u3046\u8a00\u308f\u308c\u3066\u3001\u306f\u3058\u3081\u3066\u89e6\u308c\u3066\u307f\u308b\u3002<\/p>\n\n\n\n<p>\u81ea\u5206\u3067\u306f\u307e\u3063\u305f\u304f\u6c17\u3065\u3044\u3066\u3044\u306a\u304b\u3063\u305f\u306e\u306b\u3001\u6307\u5148\u306b\u308f\u305a\u304b\u306a\u6e7f\u308a\u6c17\u304c\u6b8b\u308b\u3002<\/p>\n\n\n\n<p>\u75db\u307f\u306f\u3001\u305d\u306e\u3042\u3068\u304b\u3089\u8ffd\u3044\u3064\u3044\u3066\u304f\u308b\u3002<\/p>\n\n\n\n<p>\u7570\u5909\u306f\u3001\u81ea\u899a\u3088\u308a\u3082\u5148\u306b\u3001\u3069\u3053\u304b\u3067\u691c\u77e5\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u4f53\u306f\u3001\u5916\u754c\u3068\u5185\u5074\u3092\u9694\u3066\u308b\u5883\u754c\u306e\u4e0a\u306b\u6210\u308a\u7acb\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u76ae\u819a\u3084\u7c98\u819c\u304c\u7834\u308c\u308c\u3070\u3001\u4f53\u6db2\u306f\u5916\u3078\u3068\u3055\u3089\u3055\u308c\u3001\u5185\u90e8\u306e\u74b0\u5883\u306f\u63fa\u3089\u304e\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u305d\u306e\u7834\u308c\u3092\u3001\u4f53\u5185\u306e\u3069\u3053\u304c\u6700\u521d\u306b\u5bdf\u77e5\u3057\u3066\u3044\u308b\u306e\u304b\u3002<\/p>\n\n\n\n<p>\u3068\u304f\u306b\u3001\u50b7\u306e\u8fd1\u304f\u306e\u8840\u7ba1\u304c\u6570\u79d2\u306e\u3046\u3061\u306b\u62e1\u5f35\u3057\u3001\u8840\u6db2\u6210\u5206\u3092\u306b\u3058\u307e\u305b\u308b\u4ed5\u7d44\u307f\u306f\u3001\u5341\u5206\u306b\u306f\u8aac\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u306f\u3001\u50b7\u306e\u77ac\u9593\u306b\u751f\u3058\u308b\u300c\u6d78\u900f\u5727\u306e\u5909\u5316\u300d\u306b\u6ce8\u76ee\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u900f\u660e\u306a\u30bc\u30d6\u30e9\u30d5\u30a3\u30c3\u30b7\u30e5\u306e\u5e7c\u751f\u306b\u86cd\u5149\u30c7\u30ad\u30b9\u30c8\u30e9\u30f3\u3092\u6ce8\u5165\u3057\u3001\u8840\u7ba1\u306e\u6319\u52d5\u3092\u53ef\u8996\u5316\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5c3e\u3073\u308c\u3092\u5207\u9664\u3057\u305f\u306e\u3061\u3001\u4f53\u6db2\u3068\u540c\u3058\u6fc3\u5ea6\u306e\u6eb6\u6db2\u304b\u3089\u6de1\u6c34\u3078\u5207\u308a\u66ff\u3048\u308b\u3002<\/p>\n\n\n\n<p>\u5916\u304b\u3089\u6c34\u304c\u6d41\u5165\u3057\u3001\u7d44\u7e54\u306b\u6d78\u900f\u5727\u5dee\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8840\u7ba1\u5f84\u3068\u86cd\u5149\u5206\u5b50\u306e\u6f0f\u51fa\u91cf\u3092\u7d041\u6642\u9593\u8ffd\u8de1\u3057\u3001\u3055\u3089\u306b\u7279\u5b9a\u306e\u9175\u7d20\u3084\u514d\u75ab\u7d30\u80de\u3092\u6b20\u640d\u3055\u305b\u305f\u500b\u4f53\u3067\u3082\u540c\u69d8\u306b\u89b3\u5bdf\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u6de1\u6c34\u3078\u623b\u3057\u305f\u76f4\u5f8c\u3001\u8840\u7ba1\u304b\u3089\u306e\u6f0f\u51fa\u306f\u6025\u901f\u306b\u5897\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6d78\u900f\u5727\u5dee\u3092\u751f\u3058\u3055\u305b\u306a\u3051\u308c\u3070\u3001\u3053\u306e\u5909\u5316\u306f\u5927\u304d\u304f\u6291\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30a2\u30e9\u30ad\u30c9\u30f3\u9178\u4ee3\u8b1d\u306b\u95a2\u308f\u308b\u9175\u7d20Alox5a\u3084Lta4h\u3092\u6b20\u640d\u3055\u305b\u308b\u3068\u6f0f\u51fa\u306f\u7d04\u534a\u5206\u306b\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u540c\u69d8\u306e\u6291\u5236\u306f\u3001\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u3092\u9664\u53bb\u3057\u305f\u5834\u5408\u306b\u3082\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001\u597d\u4e2d\u7403\u3092\u9664\u53bb\u3057\u3066\u3082\u521d\u671f\u53cd\u5fdc\u306f\u4fdd\u305f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8840\u7ba1\u304c\u76f4\u63a5\u50b7\u3092\u611f\u3058\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u8840\u7ba1\u306e\u305d\u3070\u306b\u3044\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u304c\u4ef2\u4ecb\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u6d6e\u304b\u3073\u4e0a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u3067\u306f\u3001\u305d\u306e\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306f\u3001\u3069\u3053\u3067\u7570\u5909\u3092\u611f\u3058\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u6d78\u900f\u5727\u306e\u5909\u5316\u306f\u3001\u7d44\u7e54\u5185\u3092\u6bce\u79d2\u304a\u3088\u305d50\u30de\u30a4\u30af\u30ed\u30e1\u30fc\u30c8\u30eb\u3067\u4f1d\u308f\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u7269\u7406\u7684\u306a\u63fa\u3089\u304e\u304c\u3001\u8840\u7ba1\u5468\u56f2\u306b\u3044\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u6838\u819c\u3092\u4e00\u904e\u6027\u306b\u5f15\u304d\u4f38\u3070\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6838\u819c\u306b\u5f35\u529b\u304c\u304b\u304b\u308b\u3068\u3001cPla2\u3068\u3044\u3046\u9175\u7d20\u304c\u305d\u3053\u3078\u96c6\u307e\u308a\u3001\u30a2\u30e9\u30ad\u30c9\u30f3\u9178\u3092\u653e\u51fa\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u3053\u304b\u3089\u751f\u6210\u3055\u308c\u308b\u8102\u8cea\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u304c\u3001\u8840\u7ba1\u900f\u904e\u6027\u3092\u9ad8\u3081\u308b\u5408\u56f3\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5185\u76ae\u7d30\u80de\u306e\u6838\u306f\u540c\u3058\u8ddd\u96e2\u306b\u3042\u3063\u3066\u3082\u540c\u69d8\u306e\u5fdc\u7b54\u3092\u793a\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u5fdc\u7b54\u3057\u3066\u3044\u308b\u306e\u306f\u3001\u8840\u7ba1\u306e\u8fd1\u304f\u306b\u3044\u308b\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306e\u6838\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u6838\u3068\u3044\u3048\u3070\u3001\u907a\u4f1d\u60c5\u5831\u3092\u53ce\u3081\u305f\u5834\u6240\u3068\u6559\u308f\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>DNA\u3092\u5b88\u308a\u3001\u8ee2\u5199\u3092\u5236\u5fa1\u3059\u308b\u4e2d\u5fc3\u90e8\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u3053\u306e\u7814\u7a76\u304c\u63cf\u304d\u51fa\u3059\u6838\u306f\u3001\u305d\u308c\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u6838\u306f\u3001\u5f62\u306e\u5909\u5316\u3092\u8aad\u3080\u69cb\u9020\u3067\u3082\u3042\u308b\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u819c\u304c\u5f15\u304d\u4f38\u3070\u3055\u308c\u308b\u3068\u3044\u3046\u7269\u7406\u7684\u306a\u6b6a\u307f\u3092\u3001\u8102\u8cea\u30b7\u30b0\u30ca\u30eb\u3078\u3068\u5909\u63db\u3059\u308b\u88c5\u7f6e\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306e\u5009\u5eab\u3067\u3042\u308b\u524d\u306b\u3001\u529b\u3092\u53d7\u3051\u53d6\u308a\u3001\u7ffb\u8a33\u3059\u308b\u5b58\u5728\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u5883\u754c\u304c\u7834\u308c\u305f\u3068\u304d\u3001\u6700\u521d\u306b\u63fa\u3089\u3050\u306e\u306f\u7d30\u80de\u5916\u6db2\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u6838\u819c\u3082\u307e\u305f\u3001\u308f\u305a\u304b\u306b\u5909\u5f62\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u5909\u5f62\u304c\u3001\u8840\u7ba1\u3078\u3068\u4f1d\u308f\u308b\u5316\u5b66\u7684\u306a\u6ce2\u3092\u751f\u3080\u3002<\/p>\n\n\n\n<p>\u708e\u75c7\u306e\u59cb\u307e\u308a\u306f\u3001\u75db\u307f\u3067\u3082\u8d64\u307f\u3067\u3082\u306a\u304f\u3001\u6838\u306e\u6a5f\u68b0\u7684\u306a\u5fdc\u7b54\u306b\u3042\u308b\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u3082\u3061\u308d\u3093\u3001\u3053\u306e\u89b3\u5bdf\u306f\u9b5a\u306e\u5e7c\u751f\u3067\u306e\u7d50\u679c\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u54fa\u4e73\u985e\u306b\u3069\u3053\u307e\u3067\u5171\u6709\u3055\u308c\u3066\u3044\u308b\u304b\u306f\u3001\u307e\u3060\u308f\u304b\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3001\u7269\u7406\u7684\u306a\u4f38\u5c55\u3068\u708e\u75c7\u304c\u7d50\u3073\u3064\u304f\u73fe\u8c61\u306f\u4ed6\u306e\u7d44\u7e54\u3067\u3082\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6838\u304c\u5f62\u3092\u611f\u3058\u53d6\u308b\u3068\u3044\u3046\u6027\u8cea\u306f\u3001\u3088\u308a\u5e83\u3044\u751f\u7269\u5b66\u7684\u539f\u7406\u306e\u4e00\u90e8\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u8033\u306e\u5f8c\u308d\u306e\u5c0f\u3055\u306a\u50b7\u306b\u3001\u81ea\u5206\u3067\u306f\u6c17\u3065\u3051\u306a\u304b\u3063\u305f\u3042\u306e\u77ac\u9593\u3002<\/p>\n\n\n\n<p>\u4f53\u306e\u5185\u90e8\u3067\u3082\u3001\u3069\u3053\u304b\u304c\u5148\u306b\u63fa\u3089\u304e\u3092\u8aad\u3093\u3067\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u6838\u306f\u3001\u6c88\u9ed9\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3002<\/p>\n\n\n\n<p>\u5f62\u304c\u5909\u308f\u308b\u305f\u3073\u306b\u3001\u5916\u754c\u306e\u51fa\u6765\u4e8b\u3092\u7ffb\u8a33\u3057\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u751f\u304d\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u5883\u754c\u3092\u5b88\u308b\u3053\u3068\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u305d\u306e\u5883\u754c\u306e\u6b6a\u307f\u3092\u3001\u6838\u304c\u611f\u3058\u7d9a\u3051\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u306a\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n\n<p><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/p>\n\n\n\n<p><strong>Gelashvili, Z., Shen, Z., Ma, Y.&nbsp;<em>et al.<\/em>&nbsp;Zebrafish macrophages convert physical wound signals into rapid vascular permeabilization.&nbsp;<em>Nat Commun<\/em>&nbsp;(2026). <a href=\"https:\/\/doi.org\/10.1038\/s41467-026-68520-2\">https:\/\/doi.org\/10.1038\/s41467-026-68520-2<\/a><\/strong><\/p>\n\n\n\n<p>\u3000<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"400\" src=\"https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2026\/02\/Zebrafish-macrophages-convert-physical-wound-signals-into-rapid-vascular-permeabilization.jpg\" alt=\"\" class=\"wp-image-28953\" srcset=\"https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2026\/02\/Zebrafish-macrophages-convert-physical-wound-signals-into-rapid-vascular-permeabilization.jpg 600w, https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2026\/02\/Zebrafish-macrophages-convert-physical-wound-signals-into-rapid-vascular-permeabilization-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n<\/div>\n\n\n<p>\u3000<\/p>\n\n\n\n<p>\u7d39\u4ecb\u3057\u305f\u8ad6\u6587\u306e\u97f3\u58f0\u6982\u8981\u3092\u3001NotebookLM\u3067\u30dd\u30c3\u30c9\u30ad\u30e3\u30b9\u30c8\u5316\u3057\u3066\u307f\u307e\u3057\u305f\u3002\u3042\u308f\u305b\u3066\u304a\u697d\u3057\u307f\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n\n\n<p>\u3000<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3000 \u300c\u305d\u3053\u3001\u8033\u306e\u5f8c\u308d\u3001\u5c11\u3057\u8840\u304c\u51fa\u3066\u308b\u3088\u300d \u3000 \u305d\u3046\u8a00\u308f\u308c\u3066\u3001\u306f\u3058\u3081\u3066\u89e6\u308c\u3066\u307f\u308b\u3002 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