{"id":26697,"date":"2025-03-03T07:36:00","date_gmt":"2025-03-02T22:36:00","guid":{"rendered":"https:\/\/sakuda-clinic.com\/doctor\/?p=26697"},"modified":"2025-02-26T20:13:48","modified_gmt":"2025-02-26T11:13:48","slug":"%e3%81%bf%e3%81%8b%e3%82%93%e3%82%92%e9%a3%9f%e3%81%b9%e3%82%8b%e3%81%a8%e6%b0%97%e5%88%86%e3%82%92%e3%81%82%e3%81%92%e3%81%a6%e3%81%8f%e3%82%8c%e3%82%8b%e3%81%8b%e3%82%82%e7%9f%a5%e3%82%8c%e3%81%aa","status":"publish","type":"post","link":"https:\/\/sakuda-clinic.com\/doctor\/?p=26697","title":{"rendered":"\u307f\u304b\u3093\u3092\u98df\u3079\u308b\u3068\u6c17\u5206\u3092\u3042\u3052\u3066\u304f\u308c\u308b\u304b\u3082\u77e5\u308c\u306a\u3044"},"content":{"rendered":"\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u30aa\u30ec\u30f3\u30b8\u3084\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306a\u3069\u306e\u67d1\u6a58\u985e\u3092\u591a\u304f\u542b\u3080\u98df\u751f\u6d3b\u306f\u3001\u6c17\u5206\u306e\u843d\u3061\u8fbc\u307f\u3092\u548c\u3089\u3052\u3066\u304f\u308c\u305d\u3046\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">32,427\u4eba\u306e\u4e2d\u5e74\u5973\u6027\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8ffd\u8de1\u8abf\u67fb\u3067\u306f\u3001\u67d1\u6a58\u985e\u3092\u591a\u304f\u6442\u53d6\u3059\u308b\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5c11\u306a\u3044\u30b0\u30eb\u30fc\u30d7\u3068\u6bd4\u8f03\u3057\u3066\u3046\u3064\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u7d0422\uff05\u4f4e\u3044\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3053\u306e\u7d50\u679c\u306f\u3001\u98df\u4e8b\u30d1\u30bf\u30fc\u30f3\u3084\u4f53\u683c\u6307\u6570\uff08BMI\uff09\u306a\u3069\u306e\u8981\u56e0\u3092\u8003\u616e\u3057\u3066\u3082\u5909\u308f\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001207\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u526f\u6b21\u7814\u7a76\uff08Mind Body Study\uff09\u3067\u3001\u8178\u5185\u7d30\u83cc\u53e2\u306e\u907a\u4f1d\u60c5\u5831\u89e3\u6790\u3068\u8840\u6db2\u4e2d\u306e\u4ee3\u8b1d\u7269\u6e2c\u5b9a\u3092\u5b9f\u65bd\u3057\u3001\u67d1\u6a58\u985e\u306e\u6442\u53d6\u91cf\u3068\u8178\u5185\u7d30\u83cc <em>Faecalibacterium prausnitzii<\/em> \u306e\u91cf\u306b\u95a2\u9023\u304c\u3042\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><em>F. prausnitzii<\/em> \u306f\u3001\u77ed\u9396\u8102\u80aa\u9178\u306a\u3069\u306e\u5065\u5eb7\u7dad\u6301\u306b\u5f79\u7acb\u3064\u7269\u8cea\u3092\u751f\u6210\u3059\u308b\u3053\u3068\u3067\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u3053\u306e\u83cc\u306e\u91cf\u304c\u5c11\u306a\u3044\u307b\u3069\u3046\u3064\u75c5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u50be\u5411\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u307e\u305f\u3001\u7537\u6027307\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5225\u306e\u8a66\u9a13\uff08Men\u2019s Lifestyle Validation Study\uff09\u3067\u3082\u3001<em>F. prausnitzii<\/em> \u306e\u5897\u52a0\u304c\u8840\u4e2d\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u3084GABA\uff08\u03b3-\u30a2\u30df\u30ce\u916a\u9178\uff09\u306b\u95a2\u9023\u3059\u308b\u6307\u6a19\u306e\u4e0a\u6607\u3068\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3053\u308c\u3089\u306e\u6307\u6a19\u306f\u3001\u3046\u3064\u75c7\u72b6\u3092\u5224\u5225\u3059\u308b\u7cbe\u5ea6\u304cAUC 0.86\u3068\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u67d1\u6a58\u985e\u3068 <em>F. prausnitzii<\/em> \u304c\u6c17\u5206\u3084\u3046\u3064\u75c5\u30ea\u30b9\u30af\u306b\u3069\u306e\u3088\u3046\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u3001S-\u30a2\u30c7\u30ce\u30b7\u30eb-L-\u30e1\u30c1\u30aa\u30cb\u30f3\uff08SAM\uff09\u3092\u5408\u6210\u3059\u308b\u4ee3\u8b1d\u7d4c\u8def\u304c\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">SAM\u306f\u3001\u8133\u5185\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u3084\u30c9\u30fc\u30d1\u30df\u30f3\u306a\u3069\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u5408\u6210\u30fb\u8abf\u6574\u306b\u4e0d\u53ef\u6b20\u306a\u30e1\u30c1\u30eb\u57fa\u306e\u4f9b\u4e0e\u4f53\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u4e00\u90e8\u306e\u81e8\u5e8a\u7814\u7a76\u3067\u306f\u3001SAM\u306e\u88dc\u7d66\u304c\u3046\u3064\u75c7\u72b6\u306e\u6539\u5584\u306b\u5f79\u7acb\u3064\u53ef\u80fd\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u4eca\u56de\u306e\u89e3\u6790\u3067\u306f\u3001<em>F. prausnitzii<\/em> \u304c\u6301\u3064SAM\u5408\u6210\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u304c\u591a\u3044\u307b\u3069\u3001\u3046\u3064\u75c5\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u67d1\u6a58\u985e\u306b\u8c4a\u5bcc\u306a\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u306e\u4e00\u7a2e\u3067\u3042\u308b\u30ca\u30ea\u30f3\u30b2\u30cb\u30f3\u306f\u3001\u3053\u306eSAM\u5408\u6210\u9175\u7d20\u306e\u91cf\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u304a\u308a\u3001\u8178\u5185\u7d30\u83cc\u304cSAM\u3092\u7523\u751f\u3057\u3084\u3059\u3044\u72b6\u614b\u3092\u4f5c\u308a\u51fa\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3055\u3089\u306b\u3001\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u5b9f\u9a13\u3067\u306f\u3001\u8178\u5185\u3067\u751f\u6210\u3055\u308c\u305f\u30bb\u30ed\u30c8\u30cb\u30f3\u304c\u8ff7\u8d70\u795e\u7d4c\u3092\u4ecb\u3057\u3066\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u4eca\u56de\u306e\u7814\u7a76\u3067\u3082\u3001SAM\u5408\u6210\u7d4c\u8def\u304c\u6d3b\u767a\u306a\u5834\u5408\u306b\u306f\u3001\u5927\u8178\u3067\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3092\u5206\u89e3\u3059\u308b\u907a\u4f1d\u5b50\uff08MAOA\uff09\u306e\u767a\u73fe\u304c\u4f4e\u3044\u50be\u5411\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3064\u307e\u308a\u3001\u8178\u5185\u3067\u751f\u6210\u3055\u308c\u308b\u7269\u8cea\u304c\u30bb\u30ed\u30c8\u30cb\u30f3\u3084\u30c9\u30fc\u30d1\u30df\u30f3\u3092\u9069\u5207\u306b\u7dad\u6301\u3057\u3001\u5fc3\u306e\u5b89\u5b9a\u306b\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u67d1\u6a58\u985e\u3092\u6442\u53d6\u3059\u308b\u98df\u751f\u6d3b\u304c\u5fc3\u306e\u5065\u5eb7\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u305f\u3060\u3057\u3001\u3046\u3064\u75c5\u306b\u306f\u30b9\u30c8\u30ec\u30b9\u3084\u907a\u4f1d\u7684\u8981\u56e0\u306a\u3069\u3001\u591a\u5c90\u306b\u308f\u305f\u308b\u8981\u7d20\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u672c\u7814\u7a76\u306f\u89b3\u5bdf\u7814\u7a76\u3067\u3042\u308b\u305f\u3081\u3001\u76f4\u63a5\u7684\u306a\u56e0\u679c\u95a2\u4fc2\u3092\u8a3c\u660e\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3057\u304b\u3057\u3001\u9577\u671f\u306b\u308f\u305f\u308b\u8ffd\u8de1\u8abf\u67fb\u3084\u8178\u5185\u7d30\u83cc\u53e2\u306e\u907a\u4f1d\u60c5\u5831\u89e3\u6790\u3001\u8840\u4e2d\u4ee3\u8b1d\u7269\u306e\u6e2c\u5b9a\u3068\u3044\u3063\u305f\u5305\u62ec\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3088\u308a\u3001\u300c\u67d1\u6a58\u985e\u2192<em>F. prausnitzii<\/em> \u2192SAM\u7523\u751f\u2192\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u5909\u52d5\u300d\u3068\u3044\u3046\u6d41\u308c\u304c\u8003\u3048\u3089\u308c\u308b\u3053\u3068\u306f\u3001\u91cd\u8981\u306a\u767a\u898b\u3068\u8a00\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong><\/p>\n\n\n\n<p class=\"has-medium-font-size\"><strong>Samuthpongtorn, C., Chan, A.A., Ma, W.&nbsp;<em>et al.<\/em>&nbsp;<em>F. prausnitzii<\/em>&nbsp;potentially modulates the association between citrus intake and depression.&nbsp;<em>Microbiome<\/em>&nbsp;12, 237 (2024). <\/strong><a href=\"https:\/\/doi.org\/10.1186\/s40168-024-01961-3\"><strong>https:\/\/doi.org\/10.1186\/s40168-024-01961-3<\/strong><\/a><strong><\/strong><\/p>\n\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"420\" src=\"https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2025\/03\/orange.jpg\" alt=\"\" class=\"wp-image-26703\" srcset=\"https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2025\/03\/orange.jpg 600w, https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2025\/03\/orange-300x210.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-medium-font-size\">\u3000<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3000 \u30aa\u30ec\u30f3\u30b8\u3084\u30b0\u30ec\u30fc\u30d7\u30d5\u30eb\u30fc\u30c4\u306a\u3069\u306e\u67d1\u6a58\u985e\u3092\u591a\u304f\u542b\u3080\u98df\u751f\u6d3b\u306f\u3001\u6c17\u5206\u306e\u843d\u3061\u8fbc\u307f\u3092\u548c\u3089\u3052\u3066\u304f\u308c\u305d\u3046\u3067\u3059\u3002 \u3000 32,427\u4eba\u306e\u4e2d\u5e74\u5973\u6027\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8ffd\u8de1\u8abf\u67fb\u3067\u306f\u3001\u67d1\u6a58\u985e\u3092\u591a\u304f\u6442\u53d6\u3059\u308b\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5c11\u306a\u3044\u30b0\u30eb\u30fc\u30d7\u3068\u6bd4\u8f03\u3057\u3066\u3046\u3064\u75c5\u306e&hellip;<\/p>\n","protected":false},"author":2,"featured_media":26703,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9,16,27,36],"tags":[],"class_list":["post-26697","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-9","category-16","category-27","category-36"],"jetpack_featured_media_url":"https:\/\/sakuda-clinic.com\/doctor\/wp-content\/uploads\/2025\/03\/orange.jpg","jetpack_shortlink":"https:\/\/wp.me\/p3uEcz-6WB","jetpack-related-posts":[{"id":27030,"url":"https:\/\/sakuda-clinic.com\/doctor\/?p=27030","url_meta":{"origin":26697,"position":0},"title":"\u98f2\u3093\u3067\u306a\u3044\u306e\u306b\u9154\u3063\u6255\u3044\uff1f\u2015\u4e0d\u601d\u8b70\u306a\u81ea\u5bb6\u91b8\u9020\u75c7\u5019\u7fa4","author":"sakuda","date":"2025\/04\/30","format":false,"excerpt":"\u3000 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