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\u4f8b\u3048\u3070\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3067\u3082\u3001\u30b7\u30ca\u30d7\u30b9\u6a5f\u80fd\u306e\u6539\u5584\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n \u3053\u306e\u3088\u3046\u306b\u3001PHDP5\u306f\u591a\u304f\u306e\u795e\u7d4c\u5909\u6027\u75be\u60a3\u306e\u6cbb\u7642\u306b\u5fdc\u7528\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u4eca\u5f8c\u306e\u7814\u7a76\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n PHDP5\u306f\u3001\u795e\u7d4c\u7d30\u80de\u306e\u6a5f\u80fd\u3092\u56de\u5fa9\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u75c7\u72b6\u3092\u7de9\u548c\u3059\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u306e\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n \u3053\u308c\u304b\u3089\u306e\u7814\u7a76\u3067\u3055\u3089\u306b\u8a73\u7d30\u304c\u660e\u3089\u304b\u306b\u306a\u308c\u3070\u3001\u79c1\u305f\u3061\u306e\u5065\u5eb7\u3092\u5b88\u308b\u305f\u3081\u306e\u5f37\u529b\u306a\u6b66\u5668\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n \u3000<\/p>\n\n\n\n \u53c2\u8003\u8ad6\u6587\uff1a<\/strong><\/p>\n\n\n\n Chang CJ, Taoufiq Z, Yamada H, Takei K, Tomiyama T, Umeda T, Hori T, Takahashi T. The microtubule-dynamin binding inhibitor peptide PHDP5 rescues spatial learning and memory deficits in Alzheimer\u2019s disease model mice. 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